Chiralix——手性分子專業供應商

Chiralix是一家專業從事手性有機分子合成和供應的公司，我們致力于制藥公司及生命科學研究領域的實驗室研究用*手性分子的生產和研發。我們集先進的有機分子合成、過渡金屬催化、生物催化技術于一身，具備靈活與的多種手性分子合成工藝，如基團的氨基酸，疊氮酸，氨基醇及多種肽段模塊。除了提供大量的手性分子成品，我們還提供的研發服務，如復雜有機分子的合成等。

公司主要產品：

1、氨基酸類：包括各種以氨基酸為骨架的手性衍生物。

L-allysine ethylene acetal           L/D-homopropargylglycine

L/D–bishomopropargylglycine   (2S,5R)-5-hydroxypipecolic acid hydrochloride

(S/R)-4-oxopipecolic acid ethylene acetal  (S)-5-oxopipecolic acid ethylene acetal

(5S,6S)-6-amino-5-hydroxycyclohexa-1,3-dienecarboxylic acid

(S)-β3-phenylalanine          (S/R)-α-methyl-phenylglycine

D-tert-leucine

2、N-BOC保護的氨基酸骨架類

Boc-L-allysine ethylene acetal          Boc-L-homopropargylglycine

Boc-L/D-bishomopropargylglycine CHA salt

(S)-Boc-β3-phenylalanine               (S)-Boc-α-methyl-phenylglycine

Boc-D-tert-leucine

3、N-CBZ 保護的氨基酸骨架類

Cbz-L-allysine ethylene acetal         Cbz-L-homopropargylglycine

Cbz-D-homopropargylglycine        Cbz-L-bishomopropargylglycine CHA salt

Cbz-D-bishomopropargylglycine CHA salt       (S)-Cbz-β3-phenylalanine

(S)-Cbz-α-methyl-phenylglycine CHA salt         Cbz-D-tert-leucine CHA salt

4、N-FMOC 保護的氨基酸骨架類

Fmoc-L-allysine ethylene acetal  Fmoc-L-homopropargylglycine

Fmoc-D-homopropargylglycine   Fmoc-L-bishomopropargylglycine

Fmoc-D-bishomopropargylglycine   Fmoc-cyclohexylglycine

Fmoc-D-cyclohexylglycine            Fmoc-L-β-azidoalanine

Fmoc-L-γ-azidohomoalanine     Fmoc-L-δ-azidoornithine

Fmoc-L-ε-azidolysine           (S)-Fmoc-β3-phenylalanine

           (S/R)-Fmoc-α-methyl-phenylglycine    

Fmoc-D-tert-leucine

5、AZIDO氨基酸骨架類

4-azidobutanoic acid           5-azidopentanoic acid

6-azidohexanoic acid           7-azidoheptanoic acid

2-(azidomethyl)benzoic acid    3-(azidomethyl)benzoic acid

4-(azidomethyl)benzoic acid     L-azidoalanine CHA salt

D-azidoalanine CHA salt      L-azidoallylglycine CHA salt

D-azidoallylglycine CHA salt       NG-Pmc-L-azidoarginine

L-azidoasparagine DCHA salt   D-azidoasparagine DCHA salt

L/D-azidoaspartic acid mono-tert-butyl ester CHA salt

S-Trityl-L-azidocysteine CHA salt

L-azidoglutamic acid mono-tert-butyl ester CHA salt

D-azidoglutamic acid mono-tert-butyl ester CHA salt

  L-azidoglutamine DCHA salt

D-azidoglutamine DCHA salt    N-im-Trityl-L-azidohistidine CHA salt

L/D-azidoisoleucine CHA salt

L/D-azidoleucine CHA salt

L/D-azido-tert-leucine CHA salt    

L/D-azidomethionine CHA salt 

L/D-azidophenylalanine CHA salt

(S/R)-azido-α-methyl-phenylglycine

L/D-azidoserine CHA salt  

L/D-azidoserine tert-butyl ether CHA salt

L-azidothreonine CHA salt        D-azidothreonine CHA salt

L/D-azidothreonine tert-butyl ether CHA salt

L/D-azidotryptophan CHA salt

L/D-azidotyrosine CHA salt

L/D-azidotyrosine tert-butyl ether CHA salt

L-azidovaline CHA salt

Fmoc-L-β-azidoalanine   Fmoc-L-γ-azidohomoalanine

Fmoc-L-δ-azidoornithine    Fmoc-L-ε-azidolysine

6、β²氨基酸骨架類

(S/R)-β2-homoalanine HCl salt

(S/R)-β2-homoleucine HCl salt

(S/R)-β2-homophenylalanine HCl salt

(S/R)-β2-homovaline HCl salt

7、FMOC保護的β2氨基酸骨架類

(S/R)-Fmoc-β2-homoalanine

(S/R)-Fmoc-β2-homoleucine

(S/R)-Fmoc-β2-homophenylalanine

(S/R)-Fmoc-β2-homovaline

8、CHROMOGENIC 及FLUOROGENIC氨基酸

H-Arg(Boc)2-pNA                 H-Orn(Boc)-pNA

Fmoc-Orn-pNA · HCl              H-Arg(Boc)2-AMC

H-Orn(Boc)-AMC                 Fmoc-Orn-AMC · HCl

H-Lys(Boc)-AMC                       Fmoc-Lys-AMC · HCl

Bis(H-Arg(Boc)2)-rhodamine 110   Bis(H-Orn(Boc))-rhodamine 110

9、氨基乙醇及其衍生產品

2-deoxystreptamine dihydrobromide

bis(N-diazo)-tris(O-acetyl)-2-deoxystreptamine

bis(N-Boc)-2-deoxystreptamine   bis(N-Cbz)-2-deoxystreptamine

6,8a-diepi-castanospermine    (S)-allylglycinol hydrochloride

 (R)-allylglycinol hydrochloride  (S)-propargylglycinol hydrochloride

(R)-propargylglycinol hydrochloride  (S)-homopropargylglycinol hydrochloride

(R)-homopropargylglycinol hydrochloride       (S)-bishomopropargylglycinol hydrochloride

(R)-bishomopropargylglycinol hydrochloride (2S,5R)-5-hydroxypipecolic acid hydrochloride

(5S,6S)-6-amino-5-hydroxycyclohexa-1,3-dienecarboxylic acid

10、CEREULIDE & 13C6-CEREULIDE（致吐毒素及其衍生品）

cereulide (50 µg/mL in acetonitrile)

Cereulide

13C6-cereulide (20 µg/mL in acetonitrile)

13C6-cereulide

11、STRIGOLACTONES & ANALOGUES（獨腳金內酯及其類似物）

(rac)-GR24                          (±)-strigol

(±)-5-deoxystrigol              (±)-2'-epi-5-deoxystrigol

(±)-sorgolactone                           TIS108

4-Br debranone                       4-CN debranone

Nijmegen-1

12、其它產品

Abamine oxalic acid salt     RR6

2,2,2-trichloroethoxysulfonyl chloride

2,3-dimethyl-1-(2,2,2-trichloroethoxysulfuryl)imidazolium triflate

(S)-β3-phenylalanine methyl ester hydrochloride

(3R,4R)-3,4-dihydroxycyclohexa-1,5-dienecarboxylic acid

6-methylcyclohex-1-enecarboxylic acid